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Bryan Brooks Selected Research

microcystin

12/2020Higher intestinal and circulatory lactate associated NOX2 activation leads to an ectopic fibrotic pathology following microcystin co-exposure in murine fatty liver disease.
11/2020Early microcystin-LR exposure-linked inflammasome activation in mice causes development of fatty liver disease and insulin resistance.
1/2020Microcystin exposure worsens nonalcoholic fatty liver disease associated ectopic glomerular toxicity via NOX-2-MIR21 axis.
10/2019Exogenous PP2A inhibitor exacerbates the progression of nonalcoholic fatty liver disease via NOX2-dependent activation of miR21.
1/2019Environmental microcystin targets the microbiome and increases the risk of intestinal inflammatory pathology via NOX2 in underlying murine model of Nonalcoholic Fatty Liver Disease.

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Bryan Brooks Research Topics

Disease

5Non-alcoholic Fatty Liver Disease
12/2020 - 01/2019
4Inflammation (Inflammations)
12/2020 - 01/2019
2Fatty Liver
12/2020 - 11/2020
1Dysbiosis
12/2020
1Fibrosis (Cirrhosis)
12/2020
1Insulin Resistance
11/2020
1Cicatrix (Scar)
01/2020
1Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
01/2019

Drug/Important Bio-Agent (IBA)

5microcystinIBA
12/2020 - 01/2019
3cyanoginosin LR (microcystin LR)IBA
12/2020 - 01/2020
2Lactic Acid (Lactate)FDA LinkGeneric
12/2020 - 01/2019
1InflammasomesIBA
11/2020
1Glucose (Dextrose)FDA LinkGeneric
11/2020
1OxidesIBA
10/2019
1acetovanillone (apocynin)IBA
10/2019
1NADPH Oxidase 2IBA
10/2019
1pyrrolineIBA
10/2019
1CytokinesIBA
10/2019
1Reactive Oxygen Species (Oxygen Radicals)IBA
10/2019
1LeptinIBA
10/2019
1Peroxynitrous Acid (Peroxynitrite)IBA
10/2019
1Protein Phosphatase 2 (Protein Phosphatase 2A)IBA
10/2019